The accelerating complexity and contested nature of the space domain demands a transformative leap in how space systems are conceptualized, acquired, wargamed, operated, and adapted in real time. Digital twins and Full Mission Virtualization™ are not merely technological enhancements but foundational enablers of decision dominance and strategic resilience. This paper examines the scientific progression from model-based systems engineering (MBSE) to operationally synchronized digital twins and evaluates their alignment with the U.S. Space Force’s strategic imperatives outlined in Space Warfighting: A Framework for Planners. We detail the conceptual architecture, challenges, and implementation pathways for building a digitally augmented warfighting environment that seamlessly connects design intent, operational test and training, mission rehearsal, and real-time operations.